CLICK Trial — Cognitive Load Investigation of Keyboard Click

Study Summary

An exploratory clinical study investigating whether the acoustic and tactile feedback generated by mechanical keyboards can improve attention, concentration, and task performance in adults with ADHD. Participants will complete a series of computer-based tasks using keyboards with different sound and switch profiles. The study aims to determine whether specific acoustic characteristics are associated with improved focus, reduced distractibility, and enhanced productivity.

Led by Dr Diana Lam (PhD)

Eligibility Criteria

Inclusion Criteria

Adults aged 18 years and older.
Clinically diagnosed ADHD.
Regular computer users who perform typing-based tasks for work, study, or daily activities.
Able to provide informed consent.

Exclusion Criteria

Significant hearing impairment that may affect perception of keyboard sounds.
Neurological or psychiatric conditions that may substantially impact attention or cognitive performance, other than ADHD.
Current participation in another interventional research study that may affect study outcomes.
Inability to complete study procedures or computer-based assessments.

VOICE-AE Trial - Opinions on Intelligent Clinical Epilepsy

Study Summary

The VOICE-AE Trial is a mixed-methods clinical research study exploring patient and caregiver perspectives on the use of artificial intelligence (AI)–enabled tools in the management of epilepsy. These tools may include seizure prediction applications, wearable seizure detection devices, digital symptom tracking platforms, and AI-assisted clinical decision support systems.

The study aims to understand how individuals living with epilepsy perceive the usefulness, trustworthiness, usability, and safety of AI-driven technologies in their daily care. It will also examine concerns relating to privacy, autonomy, clinical decision-making, and the integration of AI tools into routine neurological care.

Led by Dr Leonardo Vincent (PhD, MD)

Eligibility Criteria

Inclusion Criteria

Adults aged 18 years and older
Clinical diagnosis of epilepsy
Experience using, or willingness to discuss, digital health or AI-enabled tools (e.g., apps, wearables, seizure tracking systems)
Able to provide informed consent
English language proficiency sufficient to complete interviews or questionnaires

Exclusion Criteria

Severe cognitive impairment preventing meaningful participation in interviews or surveys
Acute unstable medical or psychiatric condition impacting ability to participate
Inability to access or engage with digital tools (if required for specific study components)

PACIFIC & BEYOND - Patient centered clinical trials

Study Summary

The PACIFIC and BEYOND Trial is a mixed-methods clinical research study designed to explore how people living with epilepsy and their caregivers can partner with researchers to co-design more patient-centred clinical trials. The study will evaluate innovative approaches to involving patients throughout the research process, from identifying research priorities and designing study procedures to selecting meaningful outcome measures and evaluating participant experiences.

The study aims to better understand how patients and caregivers perceive and experience patient-centred clinical trial interventions. Findings from the PACIFIC and BEYOND Trial will provide evidence to support the development of more inclusive, accessible, and patient-centred clinical trials.

Led by Dr Linda Truong, M.Phil. (Medicine), B.Sc. (Hons I) (Pharmacology)

Eligibility Criteria

Inclusion Critiera

Adults aged 18 years and older
Individuals living with epilepsy or caregivers/family members of people living with epilepsy
Clinical diagnosis of epilepsy (for patient participants)
Experience participating in, or willingness to discuss, clinical research and trial participation
Willingness to provide perspectives on the design, conduct, and evaluation of patient-centred clinical trials
Able to provide informed consent
English language proficiency sufficient to participate in interviews, focus groups, workshops, or complete questionnaires

Exclusion Criteria

Severe cognitive impairment or communication difficulties preventing meaningful participation in interviews, discussions, workshops, or surveys
Acute unstable medical, neurological, or psychiatric condition that may affect the ability to participate
Inability or unwillingness to engage in study activities, including co-design discussions or completion of study assessments
Participants unable to provide informed consent and without an appropriate legally authorised representative (where applicable)

CLICK Trial — Cognitive Load Investigation of Keyboard Click

Study Summary

Eligibility Criteria

VOICE-AE Trial - Opinions on Intelligent Clinical Epilepsy

Study Summary

Eligibility Criteria

PACIFIC & BEYOND - Patient centered clinical trials

Study Summary

Eligibility Criteria

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